Secondary sex ratio in three inbred mice strains at National Laboratory Animal Center, Mahidol University

52. Kasetsart University Annual Conference

Bangkok (Thailand)

4-7 Feb 2014

Bangkok (Thailand)

p. 124-128

339 p.

อังกฤษ

Thai National AGRIS Centre, Office of The University Library Kasetsart University, P.O. BOX 1084 Kasetsart Chatuchak, Bangkok 10903, Thailand

L10-การปรับปรุงพันธุ์สัตว์

L70-สัตวแพทยศาสตร์

หนูตัวเล็ก;สัตว์ทดลองในห้องปฏิบัติการ;การผสมเลือดชิด;อัตราส่วนทางเพศ

Mice;Laboratory animals;Inbreeding;Sex ratio

หนู;สายพันธุ์ผสมเลือดชิด;อัตราส่วนเพศ

Mice;Inbred strains;Sex ratio;Secondary sex ratio

The three inbred mice strains at Nation Laboratory Animal Center's (NLAC) foundation colonies were looked for secondary sex ratios. The data were collected from all mating pair from the year 1999 to the year 2012. These 3 strains consist of BALB/cMlac, C57BL/6Mlac and DBA/2Mlac. Their sex ratios were 0.49, 0.50 and 0.52, respectively. Statistical analysis (binomial-test) indicated that secondary sex ratios of 3 inbred mice strains at NLAC do not deviate from the theoretical ratio. Moreover, they are consistent with other laboratories. This is the revelation of the common practice strong stabilizing selection for the intermediate sex ratio at NLAC's foundation colonies.

[1] Thanaporn Pinpart (Mahidol University, Bangkok (Thailand). National Laboratory Animal Centre. Office of Academic Services. Laboratory Animal Production)
[2] Apisit Laosantisuk (Mahidol University, Bangkok (Thailand). National Laboratory Animal Centre. Office of Academic Services. Laboratory Animal Production)
[3] Wanson Keawmanee (Mahidol University, Bangkok (Thailand). National Laboratory Animal Centre. Office of Academic Services. Laboratory Animal Production)
[4] Kanchana Kengkoom (Mahidol University, Bangkok (Thailand). National Laboratory Animal Centre. Office of Academic Services. Laboratory Animal Production)